Empowering peptidomics: utilizing computational tools and approaches

Bioanalysis. 2023 Nov;15(21):1315-1325. doi: 10.4155/bio-2023-0102. Epub 2023 Sep 22.

Abstract

Bioinformatics plays a critical role in the advancement of peptidomics by providing powerful tools for data analysis, interpretation and integration. Peptidomics is concerned with the study of peptides, short chains of amino acids with diverse biological functions. This area includes peptide identification and characterization, database construction, de novo sequencing, functional annotation, omics data integration and systems biology. Artificial intelligence techniques, such as machine learning and natural language processing, aid in the interpretation of peptide sequence data and the generation of biological insights. By using bioinformatics approaches, peptidomics researchers can accelerate peptide discovery, understand their functions and gain insights into complex molecular interactions.

Keywords: bioinformatics; data analysis; data integration peptidomics.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Artificial Intelligence*
  • Computational Biology / methods
  • Peptides* / chemistry
  • Power, Psychological

Substances

  • Peptides