Pertussis outbreak mainly in unvaccinated young children in ultra-orthodox Jewish groups, Jerusalem, Israel 2023

Epidemiol Infect. 2023 Sep 22:151:e166. doi: 10.1017/S0950268823001577.

Abstract

Despite being a vaccine-preventable disease for decades, pertussis control is still a public health challenge. A pertussis outbreak emerged in Jerusalem (n = 257 cases, January to June 2023). Most cases were young children (median age 1.5 years), and 100 were infants under 1 year. The hospitalisation rate of infants was 24%, which was considerably higher than that of cases aged 1 year and above (3.8%). There was one fatality in an unvaccinated, 10-week-old infant whose mother had not received pertussis vaccination during pregnancy. Most children were unvaccinated and resided in Jewish ultra-orthodox neighbourhoods in Jerusalem district. An intervention programme and vaccination campaign are ongoing.

Keywords: Bordetella pertussis; outbreak; pertussis (whooping; cough); ultra-orthodox; vaccines.

MeSH terms

  • Child
  • Child, Preschool
  • Disease Outbreaks / prevention & control
  • Female
  • Humans
  • Infant
  • Israel / epidemiology
  • Jews
  • Pertussis Vaccine
  • Vaccination
  • Whooping Cough* / epidemiology
  • Whooping Cough* / prevention & control

Substances

  • Pertussis Vaccine