Surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery in China

Jing-Bin Huang; Chang-Chao Lu; Zhao-Ke Wen; Jian-Rong Yang; Jun-Jun Li

doi:10.3389/fcvm.2023.1217148

Surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery in China

Front Cardiovasc Med. 2023 Sep 6:10:1217148. doi: 10.3389/fcvm.2023.1217148. eCollection 2023.

Authors

Jing-Bin Huang¹, Chang-Chao Lu¹, Zhao-Ke Wen¹, Jian-Rong Yang¹, Jun-Jun Li¹

Affiliation

¹ Department of Cardiothoracic Surgery, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, China.

Abstract

Introduction: We aimed to investigate surgical treatment of left-sided infective endocarditis with symptomatic neurological complications before surgery.

Methods: This was a retrospective study of patients with left-sided infective endocarditis and symptomatic neurological complications before surgery undergoing cardiac surgery between January 2006 and November 2022 at our hospital.

Results: Eight hundred thirty-two patients were divided into group with symptomatic neurological complications before surgery (n = 112) and without symptomatic neurological complications before surgery (n = 720). There were 48 operative deaths (5.4%). Univariate and multivariate analyses showed that symptomatic neurological complications before surgery is statistically significantly associated with in-hospital mortality following cardiac surgery and prolonged intubation time.

Conclusions: Our study showed that symptomatic neurological complications before surgery are associated with increased in-hospital mortality following cardiac surgery and prolonged intubation time.

Keywords: left-sided infective endocarditis; mortality; neurological complications before surgery; prolonged intubation time; surgery.

Grants and funding

This work was supported by the Natural Science Foundation of China (No: 81360014), the Natural Science Foundation of Guangxi (No: 2014GXNSFAA118234), the Guangxi Key Scientific and Technological project (No: 2013BC26236), and the Projects in Guangxi Health Department (No: GZPT13-27).