Systematic Resection of the Visible Scar After Incomplete Endoscopic Resection of Rectal Neuroendocrine Tumors

Am J Gastroenterol. 2024 Feb 1;119(2):378-381. doi: 10.14309/ajg.0000000000002516. Epub 2023 Oct 2.

Abstract

Introduction: When initial resection of rectal neuroendocrine tumors (r-NETs) is not R0, persistence of local residue could lead to disease recurrence. This study aimed to evaluate the interest of systematic resection of non-R0 r-NET scars.

Methods: Retrospective analysis of all the consecutive endoscopic revisions and resections of the scar after non-R0 resections of r-NETs.

Results: A total of 100 patients were included. Salvage endoscopic procedure using endoscopic submucosal dissection or endoscopic full-thickness resection showed an R0 rate of near 100%. Residual r-NET was found in 43% of cases.

Discussion: In case of non-R0 resected r-NET, systematic scar resection by endoscopic full-thickness resection or endoscopic submucosal dissection seems necessary.

MeSH terms

  • Cicatrix / etiology
  • Cicatrix / pathology
  • Endoscopic Mucosal Resection* / methods
  • Humans
  • Neoplasm Recurrence, Local / surgery
  • Neuroendocrine Tumors* / surgery
  • Rectal Neoplasms* / pathology
  • Rectal Neoplasms* / surgery
  • Retrospective Studies
  • Treatment Outcome