CT Findings of Undifferentiated Pancreatic Cancer With Osteoclast-Like Giant Cells: A Case Series from a Single Center's Experience With 10 Cases

Zhihong Lan; Weipeng Chen; Xiangrong Yu; Guofeng Zhou

doi:10.7759/cureus.43798

CT Findings of Undifferentiated Pancreatic Cancer With Osteoclast-Like Giant Cells: A Case Series from a Single Center's Experience With 10 Cases

Cureus. 2023 Aug 20;15(8):e43798. doi: 10.7759/cureus.43798. eCollection 2023 Aug.

Authors

Zhihong Lan¹, Weipeng Chen¹, Xiangrong Yu¹, Guofeng Zhou²

Affiliations

¹ Department of Radiology, Zhuhai Hospital Affiliated with Jinan University, Zhuhai People's Hospital, Zhuhai, CHN.
² Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, CHN.

Abstract

Little is known about the imaging features of undifferentiated carcinoma with osteoclast-like giant cells of the pancreas (UCOGCP) because of its extremely low incidence. To improve the diagnostic accuracy of this tumor, 10 UCOGCP cases with confirmed histopathology were collected and their clinical and image data features were analyzed. We found that the median age of our study was 61 years (50-76 years in range) and the main clinical manifestations were nonspecific abdominal pain. There were some differences in the degree of enhancement and computed tomography (CT) features between the tumor located at the head and body or tail of the pancreas. Perhaps these subtle imaging findings can provide valuable diagnostic information.

Keywords: case series; computed tomography (ct); diagnosis; pancreas; undifferentiated pancreatic cancer with osteoclast like giant cells.

Grants and funding

This work was supported by the National Natural Science Foundation of China (grant no.: 81901729).