Effectiveness of integrated approach of yoga therapy versus usual care in management on chronic low back pain patients: A randomized controlled pilot study

Spoorthi Poojari; Deepanshu Dhiman; Babita Ghai; Deepali Mathur; Kashinath Metri; Ketan Kataria; Akshay Anand

doi:10.1111/papr.13296

Effectiveness of integrated approach of yoga therapy versus usual care in management on chronic low back pain patients: A randomized controlled pilot study

Pain Pract. 2024 Feb;24(2):248-260. doi: 10.1111/papr.13296. Epub 2023 Sep 19.

Authors

Spoorthi Poojari¹, Deepanshu Dhiman², Babita Ghai³, Deepali Mathur⁴, Kashinath Metri⁵, Ketan Kataria⁶, Akshay Anand¹

Affiliations

¹ Neuroscience Research Lab, Department of Neurology, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
² Department of Anaesthesia, Dr. Y.S Parmar Medical College and Hospital, Nahan, India.
³ Department of Anaesthesia and Intensive Care, PGIMER, Chandigarh, India.
⁴ Department of Neurology, Apollo Hospitals, Bhubaneswar, India.
⁵ Swami Vivekananda Yoga Anusandhana Samsthana, Bangalore, India.
⁶ Department of Anaesthesia, Tata Memorial Cancer Institute, Mumbai, India.

PMID: 37724772
DOI: 10.1111/papr.13296

Abstract

Background: Chronic low back pain is associated with both psychological and functional limitation. Yoga therapy has been shown to improve both the aspects. The present study was planned to evaluate integrated approach of yoga therapy with usaul care.

Aims: This controlled randomized trial was done to evaluate the clinical and molecular changes resulting from integrated approach of yoga therapy (IAYT) as an adjunct regimen and compared it with usual care for the management of chronic low back pain patients.

Material and methods: We enrolled 29 adult patients with non-specific chronic low back pain (CLBP). Patients were randomly divided into two groups. The control group received the usual care of treatment as per institutional protocol. The yoga group received IAYT as an adjunct to usual care. Primary outcomes were pain intensity assessed by verbal numerical rating scale (VNRS) and functional ability assessed by Modified Oswestry Disability Index (MODI). Secondary outcomes were pain catastrophizing, quality of life, fear of movement related to CLBP, type of pain, levels of β-endorphin and TNF-α, and salivary CGRP. All parameters were measured at baseline, 1 and 3 months.

Results: A Significant decrease in VNRS score at 1 and 3 months was observed in both the groups with the yoga group showing a more significant reduction in pain over time than the control group (p = 0.036). MODI improved significantly only in the yoga group at 1 and 3 months. Intergroup comparison revealed significantly better MODI over time in the yoga group (p < 0.001). DN4, PDQ, PCS, HADS (anxiety), and Euro QOL had a statistically significant improvement at 1 and 3 months in the yoga group compared with the control group. The HADS (depression) had a statistically significant reduction scores in the yoga group at 3 months compared with the control group (p = 0.012). There was a significant reduction in TNF-α values in the yoga group compared with baseline (p = 0.004).

Conclusion: IAYT therapy helped in addressing the psychological components of pain and improved quality of life patients with chronic low back pain compared with usual care.

Keywords: Modified Oswestry Disability Index; TNF-α; chronic low back pain; integrated yoga therapy; salivary CGRP; verbal numeric rating score; β-endorphins.

Publication types

Randomized Controlled Trial

MeSH terms

Adult
Chronic Pain* / therapy
Humans
Low Back Pain* / psychology
Low Back Pain* / therapy
Phobic Disorders*
Pilot Projects
Quality of Life
Treatment Outcome
Tumor Necrosis Factor-alpha
Yoga*

Substances

Tumor Necrosis Factor-alpha

Supplementary concepts

Phobia, Specific