Successful Therapeutic Hypothermia in a Patient with Drug-Induced J Waves and Cardiac Arrest: A Case Report

Ther Hypothermia Temp Manag. 2023 Dec;13(4):230-233. doi: 10.1089/ther.2023.0041. Epub 2023 Sep 19.

Abstract

A 50-year-old man was admitted to our hospital with hypotension and bradycardia after receiving high doses of atenolol, amlodipine, and etizolam. He had a drug-induced J wave on electrocardiography and subsequently underwent cardiac arrest. The patient was successfully rescued by venoarterial extracorporeal membrane oxygenation (VA-ECMO) and a good neurological outcome was achieved with therapeutic hypothermia (TH). In patients with J waves, TH is thought to increase the J waves and cause fatal arrhythmias, but in this case, rapid cooling with VA-ECMO allowed the patient to successfully complete TH.

Keywords: J wave; beta-blocker; calcium channel blocker; extracorporeal cardiopulmonary resuscitation; therapeutic hypothermia.

Publication types

  • Case Reports

MeSH terms

  • Cardiopulmonary Resuscitation*
  • Cold Temperature
  • Extracorporeal Membrane Oxygenation*
  • Heart Arrest* / chemically induced
  • Heart Arrest* / therapy
  • Humans
  • Hypothermia, Induced*
  • Male
  • Middle Aged
  • Treatment Outcome