EPR investigation of gamma-irradiated FAMOSER drug for DOSIMETRIC purposes

Radiat Prot Dosimetry. 2023 Sep 18;199(14):1520-1525. doi: 10.1093/rpd/ncad041.

Abstract

Exposure to ionizing radiation can also lead to the formation of stable or unstable radicals in the structures of drugs, as in many materials. The concentrations of these radicals may show a linear dependence on the radiation dose exposed. Since drugs are materials that can be found next to or on radiation victims during a possible nuclear or radiological accident, it is very meaningful to determine the Electron Paramagnetic Resonance (EPR) dosimetric properties of stable radicals in their structures. In this study, the dosimetric properties of Famoser, which is one of the stomach-relieving drugs that people often have with them in their daily life, in the dose range of 10-800 Gy were investigated by EPR technique.

MeSH terms

  • Electron Spin Resonance Spectroscopy
  • Gamma Rays
  • Humans
  • Radiation, Ionizing
  • Radiology*
  • Radiometry*