The prospective association between the use of E-cigarettes and other psychoactive substances in young people: A systematic review and meta-analysis

Neurosci Biobehav Rev. 2023 Oct:153:105392. doi: 10.1016/j.neubiorev.2023.105392. Epub 2023 Sep 14.

Abstract

The use of electronic cigarettes by young people has increased exponentially in the past decade due to various health and social influences. E-cigarettes, particularly those containing nicotine, can cause health complications and addiction, which may result in a subsequent initiation of psychoactive substance use. This systematic review and meta- analysis evaluated the prospective association between e-cigarette use and subsequent use of psychoactive substances in young people aged 10-24 years. Pooling of data from the identified longitudinal studies showed that ever e-cigarette users have an increased likelihood for subsequent cannabis, alcohol, and unprescribed Ritalin/Adderall use compared to never e-cigarette users. The findings indicate a need for interventions to reduce e-cigarette use in adolescents and young adults.

Keywords: adolescents; e-cigarettes; psychoactive substances; vaping; young people.

Publication types

  • Meta-Analysis
  • Systematic Review
  • Review

MeSH terms

  • Adolescent
  • Cognition
  • Electronic Nicotine Delivery Systems*
  • Hallucinogens*
  • Humans
  • Nicotine
  • Vaping* / adverse effects
  • Young Adult

Substances

  • Nicotine
  • Hallucinogens