Effect of perioperative airway management on postoperative outcomes of colorectal cancer patients with sarcopenia

Tingting Xie; Liyuan Li; Xiangxiang Yang; Xiaofen Wu; Minmin Wang; Weizhe Chen; Qiantong Dong; Xiaolei Chen; Jiang Li

doi:10.1016/j.ejon.2023.102418

Effect of perioperative airway management on postoperative outcomes of colorectal cancer patients with sarcopenia

Eur J Oncol Nurs. 2023 Oct:66:102418. doi: 10.1016/j.ejon.2023.102418. Epub 2023 Sep 9.

Authors

Tingting Xie¹, Liyuan Li¹, Xiangxiang Yang¹, Xiaofen Wu¹, Minmin Wang¹, Weizhe Chen², Qiantong Dong³, Xiaolei Chen⁴, Jiang Li⁵

Affiliations

¹ Department of Gastrointestinal Surgery Nursing Unit, Ward 442, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
² Department of Gastrointestinal Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
³ Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
⁴ Department of Gastrointestinal Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. Electronic address: chenxiaolei0577@126.com.
⁵ Department of Gastrointestinal Surgery Nursing Unit, Ward 442, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. Electronic address: lijiang119@163.com.

PMID: 37713967
DOI: 10.1016/j.ejon.2023.102418

Abstract

Background: It is common for colorectal cancer patients to have sarcopenia as a comorbidity, which has been shown to have a negative impact on prognosis after surgery. This study explored whether implementing a novel care program could improve postoperative outcomes in colorectal cancer patients with sarcopenia.

Methods: We retrospectively analyzed the clinical data of patients diagnosed with sarcopenia before undergoing radical colorectal cancer surgery. We divided the patients into two groups according to the time point of program implementation and, compared the clinical characteristics and postoperative outcomes of these two groups.

Results: A total of 227 patients were included in the study. The baseline clinical characteristics of the two groups were similar. Compared with the control group, patients in the implementation group had a significantly lower rate of total complications (18.5% vs. 30.3%, P = 0.041), a significantly lower rate of pulmonary complications (2.8% vs. 10.9%, P = 0.017), and a significantly shorter postoperative hospital stay (12 days vs. 14 days, P = 0.001). Implementation of perioperative airway management (P = 0.018) was shown to be a protective factor against pulmonary complications in colorectal cancer patients with sarcopenia.

Conclusion: The perioperative airway management program implemented at our center was easy to perform and can effectively improve short-term postoperative outcomes in colorectal cancer patients with sarcopenia.

Keywords: Colorectal cancer; Postoperative outcomes; Pulmonary function exercise; Sarcopenia.