In this work we study in detail core-to-core coupling effects in multicore fibers (MCFs) using a simulation tool based on supermodal interference. We pay particular attention to the impact of core area scaling, which plays an important role in prospective amplifier systems. We consider geometrical and optical properties of the MCF structure, including the ability for dense packaging of the cores but also the influence on the core guidance (V-parameter). In general, this study is important to unlock the power and energy scaling potential of the next-generation MCF amplifiers.