Cow's milk-based infant formula supplements in breastfed infants and primary prevention of cow's milk allergy: A commentary of the Committee on Nutrition of the French Society of Pediatrics

Arch Pediatr. 2023 Nov;30(8):591-594. doi: 10.1016/j.arcped.2023.07.005. Epub 2023 Sep 14.

Abstract

The role of nutritional interventions for the primary prevention of cow's milk allergy (CMA) remains debated as well as the role of early introduction of allergenic foods, which is largely encouraged from the beginning of complementary feeding. Considering the introduction of cow's milk protein (CMP), current recommendations suggest avoidance of any cow's milk formula (CMF) supplements in breastfed infants in the maternity ward. By contrast, based on poor evidence, some authors support systematic supplements of CMP in breastfed children at risk of allergy from the first week of life. The Committee on Nutrition of the French Society of Pediatrics considers that such a proposal requires more clinical studies and mainly randomized and placebo-controlled clinical trials before becoming a recommendation.

Keywords: Breastfeeding; Cow's milk protein allergy; Cow's milk supplements; Infants; Maternity; Prevention.

MeSH terms

  • Allergens
  • Animals
  • Breast Feeding
  • Cattle
  • Child
  • Female
  • Humans
  • Infant
  • Infant Formula
  • Milk
  • Milk Hypersensitivity* / prevention & control
  • Pregnancy
  • Primary Prevention

Substances

  • Allergens