Pulmonary tuberculosis and neurologic melioidosis coinfection-first case report from Madurai

Indian J Med Microbiol. 2023 Nov-Dec:46:100458. doi: 10.1016/j.ijmmb.2023.100458. Epub 2023 Sep 12.

Abstract

Despite tuberculosis and melioidosis being endemic in many countries, coinfections are unusual. Only fourteen cases of tuberculosis melioidosis coinfections have been reported. To the best of our knowledge, this is the first case of coinfection of tuberculosis and neurologic melioidosis. We report a case of 48 year diabetic male presented with fever, headache and altered sensorium for two days. On examination, there was scalp abscess with subgaleal hematoma, pus culture of which grew B. pseudomallei. Sputum culture grew the same and sputum tuberculosis PCR was positive. Patient was concurrently treated for both the conditions and recovered.

Keywords: Neurologic melioidosis; Scalp abscess; Tuberculosis with melioidosis.

Publication types

  • Case Reports

MeSH terms

  • Burkholderia pseudomallei*
  • Coinfection* / diagnosis
  • Humans
  • India
  • Male
  • Melioidosis* / complications
  • Melioidosis* / diagnosis
  • Melioidosis* / drug therapy
  • Tuberculosis* / diagnosis
  • Tuberculosis, Pulmonary* / complications
  • Tuberculosis, Pulmonary* / diagnosis