Phytochemical content, antioxidant properties, and antibacterial activities of Centella asiatica L

Nat Prod Res. 2023 Sep 14:1-6. doi: 10.1080/14786419.2023.2258439. Online ahead of print.

Abstract

The present study is an evaluation of Centella asiatica ethanolic extract in terms of total phenolic content, total flavonoids, total flavonols, anthocyanin, antioxidants, and antibacterial activities. Centella asiatica plants were collected from Guilan province, Iran. High-performance liquid chromatography-Diode array detector analysis demonstrated that the ethanolic extract of C. asiatica contained phenolic substances such as sinapic acid, catechin, quercetin, p-coumaric acid, hesperidin, eugenol, and hesperetin. The predominant phenolic compound in the extract was hesperetin. The antibacterial activities of the extract were highly potent against S. aureus and B. cereus. These findings suggest that C. asiatica is rich in phenolic compounds and can be utilised for future cosmetic and pharmaceutical purposes.

Keywords: Anti-bacterial activity; Centella asiatica; antioxidant activity; phenolic compounds.