Pharmaceutical/Biomedical applications of electrospun nanofibers - Comprehensive review, attentive to process parameters and patent landscape

Pharm Nanotechnol. 2023 Sep 11. doi: 10.2174/2211738511666230911163249. Online ahead of print.

Abstract

Nanotechnology is a new science and business endeavour with worldwide economic benefits. Growing knowledge of nanomaterial fabrication techniques has increased the focus on nanomaterial preparation for various purposes. Nanofibers are one-dimensional nanomaterials having distinct physicochemical properties and characteristics. Nanofibers are nanomaterial types with a cross-sectional dimension of tens to hundreds of nanometres. They may create high porosity mesh networks with significant interconnections among pores, making them suitable for advanced applications. Electrospinning stands out for its ease of use, flexibility, low cost, and variety among the approaches described in the literature. The most common method for making nanofibers is electrospinning. This article extensively describes and summarizes the impact of various process variables on the fabrication of nanofibers. Special attention has been given to scientific and patent prospection to confirm the research interests in nanofibers.

Keywords: Diabetic Wounds; Electrospinning.; Nanofibers; Wound Dressings.