Advances in the extracellular signal-regulated kinase signaling pathway in silkworms, Bombyx mori (Lepidoptera)

Arch Insect Biochem Physiol. 2023 Dec;114(4):e22054. doi: 10.1002/arch.22054. Epub 2023 Sep 12.

Abstract

Signaling pathways regulate the transmission of signals during organism growth and development, promoting the smooth and accurate completion of numerous physiological and biochemical reactions. The extracellular signal-regulated kinase (ERK) signaling pathway is an essential pathway involved in regulating various physiological processes, such as cell proliferation, differentiation, adhesion, migration, and more. This pathway also contributes to several important physiological processes in silkworms, including protein synthesis, reproduction, and immune defense against pathogens. Organizing related studies on the ERK signaling pathway in silkworms can provide a better understanding of its mechanism in Lepidopterans and develop a theoretical foundation for improving cocoon production and new strategies for pest biological control.

Keywords: Bombyx mori; ERK; physiological functions; regulatory mechanism.

Publication types

  • Review

MeSH terms

  • Animals
  • Bombyx* / genetics
  • Extracellular Signal-Regulated MAP Kinases* / physiology
  • Lepidoptera*
  • Signal Transduction

Substances

  • Extracellular Signal-Regulated MAP Kinases