Update on Transcatheter Treatment of Mitral and Tricuspid Valve Regurgitation

Curr Cardiol Rep. 2023 Oct;25(10):1361-1371. doi: 10.1007/s11886-023-01954-y. Epub 2023 Sep 12.

Abstract

Purpose of review: Mitral and tricuspid regurgitation represents a clinical challenge. They are associated with a poor prognosis, and many patients are not eligible for conventional surgery. Transcatheter therapies have been the focus of numerous studies and devices over the past decade. Here, we provide a summary of current options for transcatheter treatment of these 2 entities.

Recent findings: Recent studies have demonstrated the benefits of edge-to-edge repair for increasing numbers of patients. Encouraging early results with transcatheter valve replacement are also becoming available. To date, transcatheter edge-to-edge repair is currently the first-line transcatheter treatment for both mitral and tricuspid regurgitation for many patients who are not candidates for surgery. A number of transcatheter replacement devices are under development and clinical investigation but, for the most part, their current use is limited to compassionate cases or clinical trials.

Keywords: Mitral regurgitation; TEER; TMVR; TTVR; Transcatheter edge to edge repair; Transcatheter valve replacement; Tricuspid regurgitation.

Publication types

  • Review

MeSH terms

  • Cardiac Catheterization / methods
  • Heart Valve Prosthesis Implantation* / methods
  • Humans
  • Mitral Valve / diagnostic imaging
  • Mitral Valve / surgery
  • Mitral Valve Insufficiency* / surgery
  • Treatment Outcome
  • Tricuspid Valve Insufficiency* / diagnostic imaging
  • Tricuspid Valve Insufficiency* / surgery