Recent applications and future prospects of magnetic biocatalysts

Rafael Leandro Fernandes Melo; Misael Bessa Sales; Viviane de Castro Bizerra; Paulo Gonçalves de Sousa Junior; Antônio Luthierre Gama Cavalcante; Tiago Melo Freire; Francisco Simão Neto; Muhammad Bilal; Teofil Jesionowski; João Maria Soares; Pierre Basílio Almeida Fechine; José Cleiton Sousa Dos Santos

doi:10.1016/j.ijbiomac.2023.126709

Recent applications and future prospects of magnetic biocatalysts

Int J Biol Macromol. 2023 Dec 31;253(Pt 3):126709. doi: 10.1016/j.ijbiomac.2023.126709. Epub 2023 Sep 9.

Affiliations

¹ Departamento de Engenharia Metalúrgica e de Materiais, Universidade Federal do Ceará, Campus do Pici, Bloco 729, Fortaleza CEP 60440-554, CE, Brazil; Grupo de Química de Materiais Avançados (GQMat), Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará, Campus do Pici, Fortaleza CEP 60451-970, CE, Brazil.
² Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Campus das Auroras, Redenção CEP 62790-970, CE, Brazil.
³ Departamento de Química Orgânica e Inorgânica, Centro de Ciências, Universidade Federal do Ceará, Campus Pici, Fortaleza CEP 60455-760, CE, Brazil.
⁴ Departamento de Química Analítica e Físico-Química, Centro de Ciências, Universidade Federal do Ceará, Campus Pici, Fortaleza CEP 60455-760, CE, Brazil.
⁵ Grupo de Química de Materiais Avançados (GQMat), Departamento de Química Analítica e Físico-Química, Universidade Federal do Ceará, Campus do Pici, Fortaleza CEP 60451-970, CE, Brazil; Departamento de Química Analítica e Físico-Química, Centro de Ciências, Universidade Federal do Ceará, Campus Pici, Fortaleza CEP 60455-760, CE, Brazil.
⁶ Departamento de Engenharia Química, Universidade Federal do Ceará, Campus do Pici, Bloco 709, Fortaleza CEP 60455-760, CE, Brazil.
⁷ Department of Sanitary Engineering, Faculty of Civil and Environmental Engineering, Gdansk University of Technology, G. Narutowicza 11/12 Str., 80-233 Gdansk, Poland.
⁸ Institute of Chemical Technology and Engineering, Faculty of Chemical Technology, Poznan University of Technology, Berdychowo 4, PL-60965 Poznan, Poland.
⁹ Departamento de Física, Universidade do Estado do Rio Grande do Norte, Campus Mossoró, Mossoró CEP 59610-090, RN, Brazil.
¹⁰ Instituto de Engenharias e Desenvolvimento Sustentável, Universidade da Integração Internacional da Lusofonia Afro-Brasileira, Campus das Auroras, Redenção CEP 62790-970, CE, Brazil; Departamento de Engenharia Química, Universidade Federal do Ceará, Campus do Pici, Bloco 709, Fortaleza CEP 60455-760, CE, Brazil. Electronic address: jcs@unilab.edu.br.

PMID: 37696372
DOI: 10.1016/j.ijbiomac.2023.126709

Abstract

Magnetic biocatalysts combine magnetic properties with the catalytic activity of enzymes, achieving easy recovery and reuse in biotechnological processes. Lipases immobilized by magnetic nanoparticles dominate. This review covers an advanced bibliometric analysis and an overview of the area, elucidating research advances. Using WoS, 34,949 publications were analyzed and refined to 450. The prominent journals, countries, institutions, and authors that published the most were identified. The most cited articles showed research hotspots. The analysis of the themes and keywords identified five clusters and showed that the main field of research is associated with obtaining biofuels derived from different types of sustainable vegetable oils. The overview of magnetic biocatalysts showed that these materials are also employed in biosensors, photothermal therapy, environmental remediation, and medical applications. The industry shows a significant interest, with the number of patents increasing. Future studies should focus on immobilizing new lipases in unique materials with magnetic profiles, aiming to improve the efficiency for various biotechnological applications.

Keywords: Feedstock; Immobilization; Lipase; Magnetic biocatalysts; Magnetic nanoparticles.

Publication types

Review

MeSH terms

Enzymes, Immobilized*
Lipase
Magnetic Phenomena
Magnetics
Nanoparticles*

Substances

Enzymes, Immobilized
Lipase