Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic-Erosive Oral Lichen Planus

Atul Anand Bajoria; Sangamesh Ningappa Chinnannavar; Silpiranjan Mishra; Dhirendra K Singh; Jugajyoti Pathi; Vikash K Jha

doi:10.4103/jpbs.jpbs_127_23

Comparative Evaluation of Pimecrolimus Cream 1% and Triamcinolone Aceonide Paste in Treatment of Atrophic-Erosive Oral Lichen Planus

J Pharm Bioallied Sci. 2023 Jul;15(Suppl 2):S1274-S1276. doi: 10.4103/jpbs.jpbs_127_23. Epub 2023 Apr 28.

Authors

Atul Anand Bajoria¹, Sangamesh Ningappa Chinnannavar¹, Silpiranjan Mishra¹, Dhirendra K Singh², Jugajyoti Pathi³, Vikash K Jha¹

Affiliations

¹ Department of Oral Medicine and Radiology, Kalinga Institute of Dental Sciences, KIIT University, Patia, Bhubaneswar, Odisha, India.
² Department of Periodontics, Kalinga Institute of Dental Sciences, KIIT University, Patia, Bhubaneswar, Odisha, India.
³ Department of Oral and Maxillofacial Surgery, Kalinga Institute of Dental Sciences, KIIT University, Patia, Bhubaneswar, Odisha, India.

Abstract

Objectives: This study was done to assess the effects of pimecrolimus cream 1% and triamcinolone aceonide paste in the treatment of atrophic-erosive oral lichen planus.

Materials and methods: A total of 100 patients diagnosed both clinically and histopathologically as lichen planus were considered in the present study. Subjects were classified into two groups. Group I: Patients in this group were treated with 1% pimecrolimus cream and Group II: Patients falling under this group were treated with triamcinolone acetonide in 0.1% concentration.

Results: None of the patients reported worsening clinical signs and symptoms. No significant difference in efficacy and reduction in burning sensation of either pimecrolimus or trimcinolone acetonide was present.

Conclusion: Present study found no significant difference in the efficacy of both the agents studied.

Keywords: Burning; effects; lesions; oral lichen planus; pimecrolimus; triamcinolone acetonide.