Amorphous copper(II)-cyanoimidazole frameworks as peroxidase mimics for hydrogen sulfide assay

Zijun Ding; Xiaoying Gao; Yanmei Yang; Hua Wei; Shenghong Yang; Jian Liu

doi:10.1016/j.jcis.2023.09.014

Amorphous copper(II)-cyanoimidazole frameworks as peroxidase mimics for hydrogen sulfide assay

J Colloid Interface Sci. 2023 Dec 15;652(Pt B):1889-1896. doi: 10.1016/j.jcis.2023.09.014. Epub 2023 Sep 4.

Authors

Zijun Ding¹, Xiaoying Gao², Yanmei Yang², Hua Wei³, Shenghong Yang⁴, Jian Liu⁵

Affiliations

¹ Institute of Advanced Materials, State Province Joint Engineering Laboratory of Zeolite Membrane Materials, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, China; College of Life Sciences, Jiangxi Normal University, Nanchang 330022, China.
² Institute of Advanced Materials, State Province Joint Engineering Laboratory of Zeolite Membrane Materials, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, China.
³ Shandong Provincial Key Laboratory of Molecular Engineering, School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.
⁴ Shandong Provincial Key Laboratory of Molecular Engineering, School of Chemistry and Chemical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China. Electronic address: yangsh@qlu.edu.cn.
⁵ Institute of Advanced Materials, State Province Joint Engineering Laboratory of Zeolite Membrane Materials, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, China. Electronic address: jianliu18@jxnu.edu.cn.

PMID: 37690296
DOI: 10.1016/j.jcis.2023.09.014

Abstract

Metal-organic frameworks with hierarchical porosities and exposed active sites are promising for ideal enzyme mimics. In this work, we developed a simple and feasible air oxidation strategy to prepare amorphous Cu(II)-cyanoimidazole frameworks (aCu(II)-CIFs) using CuI as the metal source in dimethylsulfoxide. Benefiting from coordination unsaturation and hierarchical porosities, aCu(II)-CIFs exhibit inherent peroxidase-mimic activity for rapid colorimetric reaction of 3,3',5,5'-tetramethylbenzidine (TMB). aCu(II)-CIFs were utilized to develop a colorimetric platform for specific H₂S assay in the range of 0.6-30 μM, achieving a limit of detection (LOD) of 0.071 μM. Structural collapse of aCu(II)-CIFs and subsequent generation of stable CuS particles, along with reducibility of H₂S, are likely responsible for suppressing TMB_ox conversion. The proposed method successfully detected H₂S in real water samples, with a relative standard deviation (RSD) lower than 8.4%. This contribution is expected to offer unique insights into the amorphization mechanisms of MOFs and their potential applications.

Keywords: Air oxidation; Amorphous Cu(II) MOFs; Colorimetric analysis; H(2)S detection; Peroxidase-mimic activity.