Computed tomography fractional flow reserve discrepancies with invasive angiography and physiology - Case series

Ilan Merdler; Itsik Ben-Dor; Hector M Garcia-Garcia; Ryan Kabir; Monvadi B Srichai-Parsia; Pavan K Reddy; Gaby Weissman; Sukhdeep Bhogal; Toby Rogers; Lowell F Satler; Ron Waksman

doi:10.1016/j.carrev.2023.08.004

Computed tomography fractional flow reserve discrepancies with invasive angiography and physiology - Case series

Cardiovasc Revasc Med. 2024 Feb:59:76-80. doi: 10.1016/j.carrev.2023.08.004. Epub 2023 Aug 12.

Authors

Affiliations

¹ Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
² Department of Cardiology, MedStar Georgetown University Hospital, Washington, DC, USA; Department of Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
³ Department of Cardiology, MedStar Georgetown University Hospital, Washington, DC, USA.
⁴ Department of Cardiology, MedStar Washington Hospital Center, Washington, DC, USA.
⁵ Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA; Cardiovascular Branch, Division of Intramural Research, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
⁶ Section of Interventional Cardiology, MedStar Washington Hospital Center, Washington, DC, USA. Electronic address: ron.waksman@medstar.net.

PMID: 37689575
DOI: 10.1016/j.carrev.2023.08.004

Abstract

Background: Computed tomography with fractional flow reserve (CT-FFR) is increasingly common in assessing coronary artery disease.

Case presentation: We report five cases of discrepancies that led to changes in treatment.

Conclusions: This report highlights discordant findings between modalities, which should be considered during the diagnostic assessment of chest pain.

Keywords: Computed tomography; Coronary angiography; Fractional flow reserve; Stenosis.

Publication types

Case Reports

MeSH terms

Computed Tomography Angiography / methods
Coronary Angiography / methods
Coronary Artery Disease* / diagnostic imaging
Coronary Artery Disease* / therapy
Coronary Stenosis* / diagnostic imaging
Coronary Stenosis* / therapy
Fractional Flow Reserve, Myocardial*
Humans
Predictive Value of Tests
Retrospective Studies
Sensitivity and Specificity
Tomography, X-Ray Computed / methods