Impact of molar incisor hypomineralization on oral health-related quality of life in 8-10 years old children: A systematic review and meta-analysis

Narjes Amrollahi; Sara Hashemi; Zahra Heidari

doi:10.1016/j.jebdp.2023.101889

Impact of molar incisor hypomineralization on oral health-related quality of life in 8-10 years old children: A systematic review and meta-analysis

J Evid Based Dent Pract. 2023 Sep;23(3):101889. doi: 10.1016/j.jebdp.2023.101889. Epub 2023 May 7.

Authors

Narjes Amrollahi¹, Sara Hashemi², Zahra Heidari³

Affiliations

¹ Dental Research Center, Department of Pediatric Dentistry, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
² Dental Students' Research Committee, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: sara_hsh76@yahoo.com.
³ Department of Epidemiology and Biostatistics, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

PMID: 37689450
DOI: 10.1016/j.jebdp.2023.101889

Abstract

Objectives: This study aimed to evaluate the impact of molar incisor hypomineralization (MIH) and its different severities on various aspects of oral health-related quality of life (OHRQoL) in children between 8 and 10 years of age.

Data sources: The search terms were chosen according to the Medical Subject Headings (MeSH) and non-MeSH. Potentially eligible studies involved the OHRQoL evaluation in 8-10 years old children with MIH. An electronic search of published studies was carried out in August 2022 on Scopus, Web of Science, and PubMed databases. Of 130 papers retrieved initially, 21 were eligible to be included in the systematic review, of which 8 were excluded. The OHRQoL questionnaires used in the studies included Caregivers Perceptions Questionnaire (CPQ) 8-10, Child Oral Health Impact Profile questionnaire, and Child Oral Impacts on Daily Performances questionnaire. Nine studies using CPQ8-10 contributed to the meta-analysis.

Results: According to meta-analysis, the results revealed that in MIH children a significant increase was observed in the total score of CPQ 810 with the pooled mean of 15.89 (95% confidence interval [CI]:8.95-22.84; P-value = .001) and in oral symptoms, functional limitation and emotional well-being domains with the pooled means of 6.25 (95% CI:4.01-8.50; P-value = .001), 3.88 (95% CI:1.93-5.83; P-value = 0.001), and 3.24 (95% CI:0.96-5.52; P-value = .01), respectively. While the increase in social well-being with the pooled mean of 1.65 (95% CI: -0.47 to 3.76; P-value = .13) was not significant. Subgroup analysis based on MIH severity showed no significant difference in OHRQoL means for all variables.

Conclusion: Suffering from MIH, negatively affected the total score and all domains of the CPQ 8-10 questionnaire, except for social well-being. Furthermore, different severities of MIH had no significant impact on OHRQoL in children.

Keywords: Children; Dental enamel hypoplasia; Health; Molar incisor hypomineralization; Quality of life.

Publication types

Meta-Analysis
Systematic Review
Review

MeSH terms

Child
Humans
Molar
Molar Hypomineralization*
Quality of Life