Sensitive fluorescent detection of o-aminophenol by hemicyanine boronic acid

Zhenming Hao; Liming Hu; Ruyu Yan; Luyu Pei; Shanyan Mo

doi:10.1016/j.saa.2023.123341

Sensitive fluorescent detection of o-aminophenol by hemicyanine boronic acid

Spectrochim Acta A Mol Biomol Spectrosc. 2024 Jan 5:304:123341. doi: 10.1016/j.saa.2023.123341. Epub 2023 Sep 4.

Authors

Zhenming Hao¹, Liming Hu¹, Ruyu Yan¹, Luyu Pei¹, Shanyan Mo²

Affiliations

¹ Faculty of Environment and Life, Beijing Key Laboratory of Environmental and Viral Oncology, Beijing University of Technology, Beijing 100124, China.
² Faculty of Environment and Life, Beijing Key Laboratory of Environmental and Viral Oncology, Beijing University of Technology, Beijing 100124, China. Electronic address: mo@bjut.edu.cn.

PMID: 37688883
DOI: 10.1016/j.saa.2023.123341

Abstract

O-Aminophenol (OAP) is widely used in various industries, but it can have severe negative impacts on both the environment and human health. Herein, we reported the development of hemicyanine boronic acid (HBA) for the fluorescent detection of OAP. The reaction of HBA with OAP produced a strong fluorescence emission at 675 nm because of the generation of tricyclic borate ester hemicyanine (TBEH). The detection was very rapid, sensitive and specific. The detection had a linear range 0.1 - 10.0 µM in ethanol with a detection limit of 60 nM in water and ethanol. The accuracy and precision of our results were successfully verified via HPLC analysis. Our study offers a valuable tool for the facile and efficient detection of OAP, with practical applications in environmental and health management.

Keywords: Fluorescent detection; Hemicyanine; Tricyclic borate ester; o-Aminophenol.