Pilot Study on the Relationship between Malnutrition and Grip Strength with Prognosis in Diabetic Foot

Nutrients. 2023 Aug 24;15(17):3710. doi: 10.3390/nu15173710.

Abstract

Sarcopenia and malnutrition have been associated in the elderly population with a poor prognosis in wound healing and with other adverse events, such as institutionalization or functional impairment. However, it is not known how these factors influence the prognosis of diabetic foot in the elderly. To answer this question, a prospective observational study of 45 patients over 65 years of age admitted with diagnoses of diabetic foot in a tertiary hospital has been conducted. All patients were assessed at admission and at 3 months after returning home to determine quality of life, pain, mobility and healing, overall hospital stay in relation to the presence of malnutrition (measured by BMI, CIPA scale and analytical parameters at admission of serum proteins and albumin), and sarcopenia measured by grip force, among other geriatric syndromes. The results found a relationship between altered sarcopenia and more pain and poorer quality of life, and altered BMI was related to a lower cure rate and worse mobility at follow-up. This study seems to indicate that, in the elderly population with diabetic foot, malnutrition and sarcopenia should be managed at the same time as the treatment of the diabetic foot itself.

Keywords: diabetic foot; malnutrition; sarcopenia.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Diabetes Mellitus*
  • Diabetic Foot*
  • Hand Strength
  • Humans
  • Malnutrition* / complications
  • Malnutrition* / diagnosis
  • Pain
  • Pilot Projects
  • Prognosis
  • Quality of Life
  • Sarcopenia*

Grants and funding

Funding has been received from Abbott Nutrition for the publication and translation of the study. This funding was not used for study design or data collection, analysis of results and interpretation; nor in the drafting of the report; nor in the decision to submit the article for publication.