[Probabilistic risk assessment of dietary exposure to lead among Chongqing residents]

Wei Sheng Yan Jiu. 2023 Jul;52(4):611-617. doi: 10.19813/j.cnki.weishengyanjiu.2023.04.015.
[Article in Chinese]

Abstract

Objective: To investigate lead contamination in commercial foods in Chongqing City, and to assess the health risk of dietary lead exposure of residents in Chongqing City.

Methods: Lead concentration data was obtained from the food safety risk monitoring system, which included a total of 2347 lead-containing food samples in 11 categories in Chongqing from 2016 to 2020. Consumption data was derived from the China Health and Nutrition Survey Project in Chongqing in 2018(3 day, 24 h dietary recall survey). The dietary exposure to lead of residents in Chongqing was calculated by the Monte Carlo simulation method and the margin of exposure(MOE) method was used to evaluate the health risk of the population.

Results: The average content of lead in 2347 food samples from 11 categories ranged from 0.0328 to 0.0363 mg/kg, with an overall detection rate of 58.5%. For people aged between 3-6, 7-17, 18-59, and ≥ 60 years, the mean dietary lead intakes in Chongqing were 0.935-1.070, 0.600-0.684, 0.367-0.416, 0.369-0.419 μg/(kg·BW·d), respectively; and the high levels of dietary lead exposure(P95) were 1.642-1.852, 1.147-1.299, 0.651-0.729, 0.659-0.740 μg/(kg·BW·d), respectively. MOE values for lead were less than 1 for age groups 3-6 and 7-17 years. Mean MOE values for lead were greater than 1 for ages 18 to 59 and ≥ 60. Cereals and their products, vegetables and their products, and meat and meat products were the main sources of dietary lead exposure, accounting for more than 85% of the total dietary lead exposure.

Conclusion: There are potential health risks of lead for residents in Chongqing.

Keywords: dietary exposure; lead; margin of exposure; probabilistic risk assessment.

Publication types

  • English Abstract

MeSH terms

  • Child, Preschool
  • China
  • Dietary Exposure* / adverse effects
  • Edible Grain
  • Humans
  • Lead*
  • Risk Assessment

Substances

  • Lead