BRAFV600E promotes DC3/monocyte differentiation in human gene-engineered HSPCs and causes multisystem histiocytosis

Leukemia. 2023 Nov;37(11):2292-2296. doi: 10.1038/s41375-023-02019-3. Epub 2023 Sep 6.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Hematopoiesis
  • Histiocytosis*
  • Humans
  • Monocytes
  • Mutation
  • Proto-Oncogene Proteins B-raf* / genetics

Substances

  • Proto-Oncogene Proteins B-raf
  • BRAF protein, human