Eosinophilic Granulomatosis With Polyangiitis Presentation After Nandrolone Withdrawal

Cureus. 2023 Aug 4;15(8):e42973. doi: 10.7759/cureus.42973. eCollection 2023 Aug.

Abstract

A 41-year-old man was admitted to the Emergency Department with bilateral numbness in lower extremities and left femoral palsy. He also reported constitutional symptoms, vomiting and non-bloody diarrhoea for the last several months. He had a previous history of eosinophilic asthma with erratic follow-up. During admission, eosinophil count was 66% of white blood cells. Sural nerve biopsy revealed vasculitis with eosinophilic infiltration. Further evaluations consisted of colonoscopy and nasal endoscopy that confirmed eosinophil infiltrates on colonic ulcers and nasal polypi. The patient was started on systemic corticosteroids and cyclophosphamide. Among his personal records, he had been taking nandrolone decanoate without medical prescription, and had withdrawn a few years before the first asthma exacerbation.

Keywords: anca associated vasculitis; anca negative vasculitis; autoimmune vasculitis; eosinophilic granulomatosis with polyangiitis (egpa); nandrolone.

Publication types

  • Case Reports