Solitary plasmacytoma of the skull base: A case report and literature review

Hanane Mansouri; Sofia Elouaouch; Zahira El Youssi; Mohammed Amine Guerrouaz; Mohamed Moukhlissi; Soufiane Berhili; Loubna Mezouar

doi:10.1016/j.radcr.2023.08.027

Solitary plasmacytoma of the skull base: A case report and literature review

Radiol Case Rep. 2023 Aug 26;18(11):3894-3898. doi: 10.1016/j.radcr.2023.08.027. eCollection 2023 Nov.

Authors

Hanane Mansouri^{1

2}, Sofia Elouaouch^{1

2}, Zahira El Youssi^{1

2}, Mohammed Amine Guerrouaz^{1

2}, Mohamed Moukhlissi^{1

2}, Soufiane Berhili^{1

2}, Loubna Mezouar^{1

2}

Affiliations

¹ Faculty of Medicine, Mohammed First University, Oujda, 60000, Morocco.
² Department of Radiotherapy, Hassan II Oncology Center, Mohammed VI University Hospital Center, Oujda, 60000, Morocco.

Abstract

Plasmacytoma of the skull base is a rare entity. We present a case of sphenoid plasmacytoma in a 51-year-old woman who had nasal obstruction, intermittent epistaxis, headaches, decreasing visual acuity, and diplopia. Computed Tomography (CT) scan and magnetic resonance imaging (MRI) showed a large heterogeneous, expansile lesion measuring 75 mm × 54 mm, centered on the sphenoidal bone and the clivus. Biopsy confirmed the diagnosis of solitary plasmacytoma after ruling out systemic spread by the initial assessment. The patient was successfully managed by external beam radiotherapy and a complete response was obtained after 12 months of follow-up.

Keywords: Diagnosis; Skull base; Solitary plasmacytoma; Sphenoid; Treatment.

Publication types

Case Reports