2-oxoglutarate-dependent dioxygenases drive expansion of steroidal alkaloid structural diversity in the genus Solanum

New Phytol. 2023 Dec;240(5):2165. doi: 10.1111/nph.19239. Epub 2023 Sep 2.

Prashant D Sonawane^{1

2}, Adam Jozwiak¹, Ranjit Barbole^{1

3

4}, Sayantan Panda^{1

5}, Bekele Abebie⁶, Yana Kazachkova¹, Sachin A Gharat¹, Ofir Ramot⁷, Tamar Unger⁸, Guy Wizler¹, Sagit Meir¹, Ilana Rogachev¹, Adi Doron-Faigenboim⁹, Marina Petreikov⁹, Arthur Schaffer⁹, Ashok P Giri^{3

4}, Tali Scherf¹⁰, Asaph Aharoni¹

¹ Department of Plant and Environmental Sciences, Weizmann Institute of Science, Rehovot, 7610001, Israel.
² Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Jena, 07745, Germany.
³ Biochemical Sciences Division, CSIR-National Chemical Laboratory, Pune, 411008, India.
⁴ Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India.
⁵ Gilat Research Center, Agricultural Research Organization (ARO), Rural Delivery Negev, 85280, Israel.
⁶ Department of Plant Pathology and Weed Research, ARO-Volcani Center, Bet Dagan, 50250, Israel.
⁷ Metabolic Insights Ltd, Ness Ziona, 7414001, Israel.
⁸ Israel Structural Proteomics Centre, Weizmann Institute of Science, Rehovot, 7610001, Israel.
⁹ Institute of Plant Sciences, ARO-Volcani Center, Rishon LeZiyyon, 7505101, Israel.
¹⁰ NMR unit, Department of Chemical Research Support, Weizmann Institute of Science, Rehovot, 7610001, Israel.

No abstract available

Keywords: Solanum; specialized metabolism; steroidal glycoalkaloids; structural diversity; tomato.

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