Ivabradine as a treatment option for junctional ectopic tachycardia in an adult female

Pacing Clin Electrophysiol. 2024 May;47(5):679-682. doi: 10.1111/pace.14812. Epub 2023 Aug 31.

Abstract

A Junctional ectopic tachycardia diagnosis was performed using two electrophysiological maneuvers in an adult female with a narrow-complex supraventricular tachycardia with a bystander AV-node slow pathway conduction, who previously underwent catheter ablation attempts for an atrio-ventricular nodal re-entrant tachycardia misdiagnosis. The first maneuver was atrial entrainment with an atrial-His-His-atrial response. The second was based on the response to a premature atrial complex delivered at different phases of the tachycardia cycle confirming that anterograde slow pathway conduction and retrograde fast pathway were not involved. Considering that verapamil, diltiazem, bisoprolol + flecainide, and nadolol were ineffective, we tried ivabradine with no sustained arrhythmias during 18-months.

Keywords: EP study; differential diagnosis; ivabradine; junctional ectopic tachycardia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Benzazepines / therapeutic use
  • Cardiovascular Agents / therapeutic use
  • Electrocardiography
  • Female
  • Humans
  • Ivabradine* / therapeutic use
  • Tachycardia, Ectopic Junctional* / drug therapy
  • Tachycardia, Ectopic Junctional* / physiopathology
  • Treatment Outcome

Substances

  • Ivabradine
  • Benzazepines
  • Cardiovascular Agents