Modular Synthesis of Phosphino Hydrazones and Their Use as Ligands in a Palladium-Catalysed Cu-Free Sonogashira Cross-Coupling Reaction

Saral Baweja; Aleksandr Kazimir; Peter Lönnecke; Evamarie Hey-Hawkins

doi:10.1002/cplu.202300454

Modular Synthesis of Phosphino Hydrazones and Their Use as Ligands in a Palladium-Catalysed Cu-Free Sonogashira Cross-Coupling Reaction

Chempluschem. 2023 Oct;88(10):e202300454. doi: 10.1002/cplu.202300454. Epub 2023 Aug 31.

Authors

Saral Baweja¹, Aleksandr Kazimir¹, Peter Lönnecke¹, Evamarie Hey-Hawkins¹

Affiliation

¹ Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Leipzig University, Johannisallee 29, 04103, Leipzig, Germany.

PMID: 37650257
DOI: 10.1002/cplu.202300454

Abstract

Invited for this month's cover is the group of Evamarie Hey-Hawkins at Leipzig University. The cover picture shows the three different bonding modes (mono-, bi- and tridentate) of the modular ligand towards palladium(II) or platinum(II), illustrated with Winston who kindly served as the model. The cat has three binding sites (mouth, front paws and hind paws = P, N and pyridine) to bind the metal dichloride fragment. When all three are used in a tridentate bonding mode, one chlorido ligand is cleaved off. Cover design by Dr. Christoph Selg. More information can be found in the Research Article by Evamarie Hey-Hawkins and co-workers.