Novel breathing pattern analysis: Symmetric Projection Attractor Reconstruction improves identification of impending COPD re-exacerbations - a retrospective cohort analysis

Miquel Serna-Pascual; Rebecca F D'Cruz; Maria Volovaya; Caroline J Jolley; Nicholas Hart; Gerrard F Rafferty; Joerg Steier; Philip J Aston; Manasi Nandi

doi:10.1183/23120541.00164-2023

Novel breathing pattern analysis: Symmetric Projection Attractor Reconstruction improves identification of impending COPD re-exacerbations - a retrospective cohort analysis

ERJ Open Res. 2023 Aug 29;9(4):00164-2023. doi: 10.1183/23120541.00164-2023. eCollection 2023 Jul.

Authors

Miquel Serna-Pascual^{1

2}, Rebecca F D'Cruz^{3

4

2}, Maria Volovaya¹, Caroline J Jolley⁴, Nicholas Hart^{3

4}, Gerrard F Rafferty⁴, Joerg Steier^{3

4}, Philip J Aston⁵, Manasi Nandi¹

Affiliations

¹ School of Cancer and Pharmaceutical Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
² These authors contributed equally.
³ Lane Fox Clinical Respiratory Physiology Research Unit, Guy's and St Thomas' NHS Foundation Trust, London, UK.
⁴ Centre for Human and Applied Physiological Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
⁵ Department of Mathematics, University of Surrey, Guildford, UK.

Abstract

Respiratory waveforms can be reduced to simple metrics, such as rate, but this may miss information about waveform shape and whole breathing pattern. A novel analysis method quantifying the whole waveform shape identifies AECOPD earlier. https://bit.ly/3M6uIEB.