From diagnosis to prognosis: A paradigm shift for multimodal imaging in assessing diabetic macular edema

Eur J Ophthalmol. 2024 Jan;34(1):7-10. doi: 10.1177/11206721231199149. Epub 2023 Aug 30.

Abstract

Diabetic macular edema (DME) is one of the leading causes of visual impairment in patients with diabetes. Multimodal imaging (MMI) has allowed a shift from DME diagnosis to prognosis. Although there are no accepted guidelines, MMI may also lead to treatment customization. Several study groups have tried to identify structural biomarkers that can predict treatment response and long-term visual prognosis. The purpose of this editorial is to review currently proposed optical coherence tomography (OCT) and optical coherence tomography angiography (OCT-A) biomarkers.

Keywords: diabetic macular edema (DME); diabetic retinopathy (DR); multimodal imaging (MMI); optical coherence tomography (OCT).

Publication types

  • Editorial

MeSH terms

  • Biomarkers
  • Diabetes Mellitus*
  • Diabetic Retinopathy* / complications
  • Fluorescein Angiography / methods
  • Humans
  • Macular Edema* / diagnostic imaging
  • Macular Edema* / etiology
  • Multimodal Imaging
  • Tomography, Optical Coherence / methods

Substances

  • Biomarkers