Editing a rice CDP-DAG synthase confers broad-spectrum resistance

Xiaoman You; Yuese Ning; Guo-Liang Wang

doi:10.1016/j.tplants.2023.08.011

Editing a rice CDP-DAG synthase confers broad-spectrum resistance

Trends Plant Sci. 2023 Dec;28(12):1344-1346. doi: 10.1016/j.tplants.2023.08.011. Epub 2023 Aug 28.

Authors

Xiaoman You¹, Yuese Ning², Guo-Liang Wang³

Affiliations

¹ State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
² State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China. Electronic address: ningyuese@caas.cn.
³ Department of Plant Pathology, Ohio State University, Columbus, OH 43210, USA. Electronic address: wang.620@osu.edu.

PMID: 37648632
DOI: 10.1016/j.tplants.2023.08.011

Abstract

Lesion mimic mutations (LMMs) often confer broad-spectrum resistance (BSR) in plants, but with significant yield penalties. Sha et al. recently demonstrated that genome editing of the rice BSR gene RESISTANCE TO BLAST1 (RBL1), encoding a cytidine diphosphate diacylglycerol (CDP-DAG) synthase involved in phospholipid biosynthesis, confers multipathogen resistance without an obvious trade-off in yield.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Cytidine Diphosphate
Diacylglycerol Cholinephosphotransferase* / genetics
Diglycerides
Mutation / genetics
Oryza* / genetics

Substances

Diacylglycerol Cholinephosphotransferase
Cytidine Diphosphate
Diglycerides