Prefrontal γ-Aminobutyric Acid Levels in Never-Medicated Individuals With Chronic Schizophrenia

JAMA Psychiatry. 2023 Oct 1;80(10):1075-1077. doi: 10.1001/jamapsychiatry.2023.3157.
No abstract available

Plain language summary

This cross-sectional study analyzes spectroscopy data for long-term, never-medicated patients with schizophrenia to examine their levels of γ-aminobutyric acid (GABA) compared with those of healthy controls.

MeSH terms

  • Glutamic Acid
  • Humans
  • Magnetic Resonance Spectroscopy
  • Prefrontal Cortex
  • Schizophrenia* / diagnosis
  • gamma-Aminobutyric Acid

Substances

  • Glutamic Acid
  • gamma-Aminobutyric Acid