Controlling Intestinal Infections and Digestive Disorders Using Probiotics

J Med Food. 2023 Oct;26(10):705-720. doi: 10.1089/jmf.2023.0062. Epub 2023 Aug 30.

Abstract

After consumption, probiotics provide health benefits to the host. Probiotics and their metabolites have therapeutic and nutritional properties that help to alleviate gastrointestinal, neurological, and cardiovascular problems. Probiotics strengthen host immunity through various mechanisms, including improved gut barrier function, receptor site blocking, competitive exclusion of pathogens, and the production of bioactive molecules. Emerging evidence suggests that intestinal bowel diseases can be fatal, but regular probiotic consumption can alleviate disease symptoms. The use and detailed description of the health benefits of probiotics to consumers in terms of reducing intestinal infection, inflammation, and digestive disorders are discussed in this review. The well-designed and controlled studies that examined the use of probiotics to reduce life-threatening activities caused by intestinal bowel diseases are also covered. This review discussed the active principles and potency of probiotics as evidenced by the known effects on host health, in addition to providing information on the mechanism of action.

Keywords: Helicobacter pylori; digestive disorders; gut barrier function; immunomodulation; nutritional attributes; probiotics.

Publication types

  • Review

MeSH terms

  • Humans
  • Inflammation
  • Probiotics* / metabolism
  • Probiotics* / therapeutic use