Fracture-related infections

Br J Hosp Med (Lond). 2023 Aug 2;84(8):1-10. doi: 10.12968/hmed.2022.0545. Epub 2023 Aug 8.

Abstract

Fracture-related infection is a serious complication which can occur following musculoskeletal injury and is associated with significant morbidity. These complications can be challenging to recognise, and experts have provided a clearer definition of fracture-related infection to help with the diagnosis and detection of these infections. This system includes clinical, radiological and laboratory-based diagnostic features which are either confirmatory or suggestive of fracture-related infection. Treatment requires a multifaceted approach with multidisciplinary involvement, and generally a combination of surgical techniques and prolonged antibiotics, the timing and choice of which should be optimised. This article provides an evidence-based review of the British Orthopaedic Association Standards for Trauma for the diagnosis and management of fracture-related infections.

Keywords: BOAST guideline; Fracture-related infection; Infection; Microbiology; Orthopaedic surgery; Trauma.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Fractures, Bone* / complications
  • Fractures, Bone* / diagnosis
  • Fractures, Bone* / therapy
  • Humans
  • Laboratories
  • Orthopedics*

Substances

  • Anti-Bacterial Agents