Secondary Neurulation Defects: Retained Medullary Cord

Adv Tech Stand Neurosurg. 2023:47:215-223. doi: 10.1007/978-3-031-34981-2_7.

Abstract

Retained medullary cord (RMC) is a defect resulting from impaired secondary neurulation. Intraoperatively, RMC is recognizable as an elongated cord-like structure caudal to the conus, that contains histologically confirmed neuroglial components and a lumen with an ependymal lining. It characteristically does not possess neurological function. This chapter aims to summarize (1) the mechanisms that lead to the occurrence of RMC; (2) the various forms of RMC, such as cystic RMC and 'possible RMC', and (3) the treatment strategies, especially untethering through limited exposure.

Keywords: Apoptosis arrest; Retained medullary cord; Secondary neurulation; Tethered cord.

MeSH terms

  • Cone-Rod Dystrophies*
  • Humans
  • Lymph Nodes
  • Neurulation*