Secretory Carcinoma of Salivary Glands: A Case Series and Review of Literature

Indian J Otolaryngol Head Neck Surg. 2023 Sep;75(3):2645-2649. doi: 10.1007/s12070-023-03560-4. Epub 2023 Mar 2.

Abstract

Mammary analogue of secretory carcinoma is a recently described entity in WHO 2017 classification of head and neck tumours. It resembles secretory carcinoma of breast. It usually affects the salivary glands and has an indolent behaviour. We reviewed five cases of Mammary analogue of secretory carcinoma in our institute and compared our results with existing literature. All the patients underwent surgical resections and appropriate adjuvant treatment. Immunohistochemistry is an alternative cost effective tool as compared to genetic testing to differentiate secretory carcinoma from its mimickers. Surgery with adequate margins followed by adjuvant therapy is the treatment of choice.

Keywords: Imunohistochemistry; Mammary analogue of secretory carcinoma; Mammoglobin; Secretory carcinoma.