Absorbed dose evaluation of a blood irradiator with alanine, TLD-100 and ionization chamber

Appl Radiat Isot. 2023 Oct:200:110981. doi: 10.1016/j.apradiso.2023.110981. Epub 2023 Aug 12.

Abstract

Irradiation of blood bags using X-ray irradiators and dosimetry services are required to ensure uniform dose levels in the range 25-50 Gy to prevent Transfusion Associated Graft versus Host Disease (TA-GvHD). An absorbed dose characterization of a Raycell MK2 X-Irradiator was performed using three different dosimetric systems. Results showed a dosimetric accuracy of the ionization chamber together with the Alanine dosimeter. TLDs measurements exhibited a small overestimation by 4% of the absorbed dose. The Dose Uniformity Ratio (DUR), between maximum and minimum dose levels in the canister, was in good agreement with the manufacturer specifications (≤1.5).

Keywords: Alanine; Blood irradiation X-Ray irradiator; Dose mapping; Ion chamber; Raycell MK2; TLD dosimetry.

MeSH terms

  • Alanine*
  • Radiation Dosimeters*

Substances

  • Alanine