Chemical Studies of Multicomponent Kidney Stones Using the Modern Advanced Research Methods

Molecules. 2023 Aug 16;28(16):6089. doi: 10.3390/molecules28166089.

Abstract

Defining the kidney stone composition is important for determining a treatment plan, understanding etiology and preventing recurrence of nephrolithiasis, which is considered as a common, civilization disease and a serious worldwide medical problem. The aim of this study was to investigate the morphology and chemical composition of multicomponent kidney stones. The identification methods such as infrared spectroscopy (FTIR), X-ray diffraction (XRD), and electron microscopy with the EDX detector were presented. The studies by the X-ray photoelectron spectroscopy (XPS) were also carried out for better understanding of their chemical structure. The chemical mapping by the FTIR microscopy was performed to show the distribution of individual chemical compounds that constitute the building blocks of kidney stones. The use of modern research methods with a particular emphasis on the spectroscopic methods allowed for a thorough examination of the subject of nephrolithiasis.

Keywords: FTIR microscopy; X-ray diffraction; X-ray photoelectron spectroscopy; infrared spectroscopy; kidney stones; scanning electron microscopy.

MeSH terms

  • Humans
  • Kidney
  • Kidney Calculi*
  • Microscopy
  • Photoelectron Spectroscopy
  • Research Design

Grants and funding

This research received no external funding.