Dynamic changes of nasal tight junctions in patients with convalescent COVID-19 with allergic rhinitis

Yating Liu; Zaichuan Wang; Limin Zhao; Xue Wang; Xinyi Li; Zhennan Qu; Yuan Zeng; Yingyue Liu; Liusiqi Hao; Mengzhe Yang; Yuling Zhang; Shujian Zhang; Qiqi Wang; Yan Li; Feng Lan; Luo Zhang

doi:10.1002/alr.23258

Dynamic changes of nasal tight junctions in patients with convalescent COVID-19 with allergic rhinitis

Int Forum Allergy Rhinol. 2024 Apr;14(4):845-849. doi: 10.1002/alr.23258. Epub 2023 Aug 25.

Authors

Yating Liu¹, Zaichuan Wang¹, Limin Zhao¹, Xue Wang¹, Xinyi Li¹, Zhennan Qu¹, Yuan Zeng¹, Yingyue Liu¹, Liusiqi Hao¹, Mengzhe Yang¹, Yuling Zhang¹, Shujian Zhang¹, Qiqi Wang^{1

2

3}, Yan Li^{1

2

3}, Feng Lan^{1

2

3}, Luo Zhang^{1

2

3}

Affiliations

¹ Departments of Otorhinolaryngology Head and Neck Surgery, and Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
² Beijing Institute of Otolaryngology, Beijing Laboratory of Allergic Diseases, Beijing Key Laboratory of Nasal Diseases, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing, China.
³ Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China.

PMID: 37624074
DOI: 10.1002/alr.23258

Abstract

Nasal tight junction module score correlates negatively to allergy module score in COVID-19. Omicron variant may slow-down tight junction restoration in patients with AR.

Keywords: COVID‐19 outbreak; Epithelial cell; SARS‐CoV‐2; Tight junction; allergic rhinitis.

MeSH terms

COVID-19*
Humans
Nasal Mucosa
Rhinitis, Allergic* / therapy
SARS-CoV-2
Tight Junctions

Supplementary concepts

SARS-CoV-2 variants

Abstract

MeSH terms

Supplementary concepts

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