Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application

Biosensors (Basel). 2023 Aug 7;13(8):795. doi: 10.3390/bios13080795.

Abstract

Although vascular stents have been widely used in clinical practice, there is still a risk of in-stent restenosis after their implantation. Combining conventional vascular stents with liquid metal-based electrodes with impedance detection, irreversible electroporation, and blood pressure detection provides a new direction to completely solve the restenosis problem. Compared with conventional rigid electrodes, liquid metal-based electrodes combine high conductivity and stretchability, and are more compliant with the implantation process of vascular stents and remain in the vasculature for a long period of time. This perspective reviews the types and development of conventional vascular stents and proposes a novel stent that integrates liquid metal-based electrodes on conventional vascular stents. This vascular stent has three major functions of prediction, detection and treatment, and is expected to be a new generation of cardiovascular implant with intelligent sensing and real-time monitoring.

Keywords: biosensor; in-stent restenosis; irreversible electroporation; liquid metal; vascular stent.

MeSH terms

  • Blood Pressure
  • Electric Conductivity
  • Electric Impedance
  • Electrodes
  • Metals*
  • Stents*

Substances

  • Metals