Use of tranexamic acid-soaked NasoPore® in the emergency department, to reduce epistaxis admissions

Clin Otolaryngol. 2023 Nov;48(6):909-914. doi: 10.1111/coa.14093. Epub 2023 Aug 23.

Abstract

Objectives: The aim of this study was to assess the efficacy of a new emergency department (ED) intervention for the management of non-traumatic, anterior epistaxis in adult patients, aiming to reduce epistaxis admissions.

Design: A new epistaxis pathway was introduced for use by ED practitioners. This was disseminated in ED through an educational campaign by the ear, nose and throat team. A tranexamic acid (500 mg/5 mL)-soaked NasoPore® packing step was introduced for epistaxis which did not terminate following 10 min of simple first aid. The pathway was utilised for adult patients presenting with non-traumatic, anterior epistaxis. Pre- and post-implementation periods were defined, and all adults attending ED with non-traumatic, anterior epistaxis were included. Pre- and post-implementation epistaxis treatment interventions, admission rates and re-attendance rates were recorded by retrospective audit and compared.

Results: In the post-implementation group, epistaxis admissions were 51.7% (p < .05) lower than in the pre-implementation group, as a proportion of the total number attending ED with epistaxis during these periods.

Conclusions: The significant reduction in epistaxis admissions demonstrates that this ED intervention is beneficial for patient outcomes.

Keywords: emergency ORL; epistaxis; evidence-based medicine; health services research; outcomes; research.

MeSH terms

  • Adult
  • Bandages
  • Emergency Service, Hospital* / statistics & numerical data
  • Epistaxis* / drug therapy
  • Epistaxis* / epidemiology
  • Epistaxis* / therapy
  • Hospitalization / statistics & numerical data
  • Humans
  • Retrospective Studies
  • Tranexamic Acid* / therapeutic use
  • United Kingdom

Substances

  • Tranexamic Acid