Comparative Analysis of Radiologic Outcomes Between Polyetheretherketone and Three-Dimensional-Printed Titanium Cages After Transforaminal Lumbar Interbody Fusion

World Neurosurg. 2023 Nov:179:e241-e255. doi: 10.1016/j.wneu.2023.08.056. Epub 2023 Aug 21.

Abstract

Objective: Transforaminal lumbar interbody fusion (TLIF) is performed worldwide with polyetheretherketone (PEEK) and titanium (Ti) cages for the treatment of degenerative lumbar diseases. The aim of this study was to compare radiologic outcomes between a PEEK and three-dimensional-printed titanium (3DP-Ti) cage after TLIF with >1 year of follow-up.

Methods: A total of 140 patients with degenerative lumbar diseases who underwent TLIF operation were included in this study. Intervertebral disc height and whole lumbar lordosis were measured and evaluated from the preoperative stage to the final follow-up. Subsidence of the cage was indicated if the cage sunk into the adjacent vertebral body or if there was a reduction in height of the fused segment by ≥3 mm during the postoperative follow-up. Migration of the cage was determined as the displacement of the interbody cage by ≥2 mm during the postoperative period. Fusion status was assessed at the 1 year and final follow-up using standard methods.

Results: Both disc height and lumbar lordosis were well maintained throughout the study period, and no significant differences were observed between PEEK and 3DP-Ti groups. Both PEEK and 3DP-Ti cages demonstrated low rates of cage subsidence, with no significant difference was noted. A significant cage migration rate was observed in the PEEK group and the revision operation was required for 2 patients. The fusion rate of this study was not found to be statistically significant, although the 3DP-Ti cage was known to have an improved fusion rate than PEEK cage after lumbar interbody fusion.

Conclusions: Radiologic results suggest that the 3DP-Ti cage may be a better interbody cage for TLIF than is the PEEK cage.

Keywords: 3D-printed titanium cage; Cage-related complications; PEEK cage; Radiologic outcomes; Transforaminal lumbar interbody fusion.

MeSH terms

  • Humans
  • Ketones
  • Lordosis* / diagnostic imaging
  • Lordosis* / surgery
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / surgery
  • Polyethylene Glycols
  • Retrospective Studies
  • Spinal Fusion* / methods
  • Titanium
  • Treatment Outcome

Substances

  • polyetheretherketone
  • Titanium
  • Polyethylene Glycols
  • Ketones