Spontaneous Recovery of Pathological Fracture Caused by Medication-Related Osteonecrosis of the Jaw

J Craniofac Surg. 2024 Jan-Feb;35(1):e14-e16. doi: 10.1097/SCS.0000000000009645. Epub 2023 Aug 22.

Abstract

Pathological fracture is one of the most serious complications in medication-related osteonecrosis of the jaw (MRONJ). This case is a report of an 87-year-old woman who had been diagnosed with pathological fracture due to MRONJ. The authors performed minimally invasive and conservative treatment, such as intraoral dressing, antibiotic therapy, and simple debridement, for patients with pathologic fractures due to MRONJ. After 1 year, the inflammatory symptoms disappeared and pathological fractures spontaneously recovered.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Bisphosphonate-Associated Osteonecrosis of the Jaw* / diagnostic imaging
  • Bisphosphonate-Associated Osteonecrosis of the Jaw* / etiology
  • Bisphosphonate-Associated Osteonecrosis of the Jaw* / therapy
  • Bone Density Conservation Agents*
  • Diphosphonates
  • Female
  • Fractures, Spontaneous*
  • Humans

Substances

  • Anti-Bacterial Agents
  • Bone Density Conservation Agents
  • Diphosphonates