Full-thickness skin regeneration beneath the exposed titanium mesh in cranioplasty: Two cases report

Medicine (Baltimore). 2023 Aug 18;102(33):e34821. doi: 10.1097/MD.0000000000034821.

Abstract

Rationale: Titanium mesh is one of the most widely used implant materials applied in cranioplasty; however, it has been reported to encounter the risk of progressive scalp thinning and implant exposure over time. Here we present 2 cases of exposed titanium mesh (TM) and unusual phenomena of full-thickness skin regeneration beneath the mesh.

Patient concerns: Two patients, 1 with an 8-year and 1 with a 2-year history of implant exposure after cranial TM implantation.

Diagnoses: The patients were diagnosed with scalp ulcers and cranial TM exposure.

Intervention: The exposed part of the implant was removed, and the full-thickness skin beneath the mesh was directly used as functional soft tissue coverage to repair the scalp defect.

Outcomes: Full recovery for both patients with cosmetic satisfaction.

Lessons: Though the exact mechanism of this epithelisation phenomenon beneath the TM remains to be elucidated, it provided a feasible choice for clinicians to reconstruct the scalp's integrity without exerting complicated procedures when dealing with similar cases.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Regeneration
  • Skin
  • Skull / surgery
  • Surgical Mesh* / adverse effects
  • Titanium* / adverse effects

Substances

  • Titanium