Prospective Advances of Extracellular Vesicles Investigation in Cardiovascular and Metabolic Research

Abstract

Extracellular vesicles (EVs) play an important role in cardiovascular and metabolic diseases through intercellular communication. Although there has been extensive research on EVs, there are still some unsolved problems in the technologies of investigation of EVs. In this chapter, we reviewed the current knowledge of EVs functions in cardiovascular and metabolic pathophysiology and EVs as biomarkers and therapeutic agents in cardiovascular and metabolic diseases. We also addressed the challenges in isolation and identification of EVs as well as challenges in visualization and tracking of EVs. By addressing these challenges, we hope to have a more in-depth understanding of the biological functions of EVs.

Keywords: Cardiovascular and metabolic diseases; Challenges; Extracellular vesicles; Technologies of investigation.