Association of Collagenous Gastritis With Helicobacter pylori Infection

Nfn Kiran; Meena Kashi; Shahbaz Khan

doi:10.7759/cureus.42172

Association of Collagenous Gastritis With Helicobacter pylori Infection

Cureus. 2023 Jul 20;15(7):e42172. doi: 10.7759/cureus.42172. eCollection 2023 Jul.

Authors

Nfn Kiran¹, Meena Kashi², Shahbaz Khan^{3

4

5

1}

Affiliations

¹ Pathology and Laboratory Medicine, Staten Island University Hospital, Staten Island, USA.
² Pathology, Staten Island University Hospital, Staten Island, USA.
³ Gastrointestinal, Hepatobiliary and Transplant Pathology, Indiana University School of Medicine, Indianapolis, USA.
⁴ Hematopathology, Northwell Health, New York, USA.
⁵ Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, USA.

Abstract

Helicobacter pylori is the most common infection and is mostly asymptomatic in infected individuals. Only a few cases of collagenous gastritis associated with H. pylori infection have been reported in the previous literature. We report a case of a 54-year-old female presenting with heartburn and epigastric pain associated with bloating, gas, and sometimes constipation. The physical examination was unremarkable with a soft, non-tender, and non-distended abdomen. Upper endoscopy showed erythema in the stomach with non-erosive gastritis. Our patient was diagnosed with H. pylori-associated chronic active gastritis with collagenous gastritis on histologic evaluation of the gastric biopsy specimen. After treatment with H. pylori eradication therapy, patients with collagenous gastritis associated with H. pylori infections showed a significant improvement in collagenous gastritis on endoscopy.

Keywords: collagenous gastritis; helicobacter pylori eradication; helicobacter pylori; immunohistochemistry(ihc); trichome stain.

Publication types

Case Reports