Application of the break-even point to express the bone dynamics around implants

Yoshihiko Hori; Yoshiyuki Amari; Hiroyuki Ohnishi; Hitoshi Seo; Yeh-Chun Chi; Daniele Botticelli; Samuel Porfirio Xavier; Shunsuke Baba

doi:10.1007/s10006-023-01176-0

Application of the break-even point to express the bone dynamics around implants

Oral Maxillofac Surg. 2023 Aug 17. doi: 10.1007/s10006-023-01176-0. Online ahead of print.

Authors

Yoshihiko Hori¹, Yoshiyuki Amari², Hiroyuki Ohnishi¹, Hitoshi Seo¹, Yeh-Chun Chi¹, Daniele Botticelli³, Samuel Porfirio Xavier⁴, Shunsuke Baba¹

Affiliations

¹ Department of Oral Implantology, Osaka Dental University, 8-1 Kuzuhahanazonocho, Hirakata, Osaka, 573-1121, Japan.
² Department of Operative Dentistry, Nihon University School of Dentistry, Tokyo, Japan.
³ ARDEC Academy, viale Giovanni Pascoli 67, 47923, Rimini, Italy. daniele.botticelli@gmail.com.
⁴ Oral and Maxillofacial Surgery and Periodontology, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

PMID: 37589916
DOI: 10.1007/s10006-023-01176-0

Abstract

Purpose: The aim of this study was to apply the break-even point concept to express the dynamics of bone formation and resorption around implants.

Methods: Published data on new bone and parent bone densities around implants from one human and three dog studies were selected and used for analysis. The break-even point (BEP) of the bone density (BD) was assessed. The BEP is the point at which, in a graph, the lines representing the formation of new bone and resorption of old bone intersect. BEP is expressed in time (x; days) of occurrence and percentage of bone (y; %) at which the break-even point occurs and illustrates the grade of bone modeling. The sooner the occurrence, the faster the bone formation in relation to the resorption of the old bone.

Results: In the marrow and cortical compartments, BEP of bone density occurred after 7.9 days (BD% 24.5%) and >30 days, respectively. Different surfaces presented similar BEP, ranging between 9.7 and 11.2 days (BD% 19.1-22.5%). BEP at implants installed in the human maxilla occurred after 29-30.4 days (BD% 28.3-29.6%).

Conclusion: The present study showed that the parameters used to express the break-even point can provide information on the influence of the model used, surface characteristics, and bone quality on bone modeling/remodeling around implants.

Keywords: Animal study; Biocompatible material; Bone formation; Collagen membrane; Histology; Osteoclasts; Sinus floor elevation.